INSTITUTE OF FOOD AND RADIATION BIOLOGY

GAMA IRRADIATION FACILITY


Background


Institute of Food and Radiation Biology has a Gamma irradiation facility. This is a relatively small unit primarily designed for research , however is also used for irradiation services. Though initially designed as 50 KCi ( fifty thousand Curie ) Source, the current strength is about 17 thousand Curie with planned replenishment very shortly to 68 Kci. Gamma sterilization is very effective for sterilizing wide variety of medical and other products and more amore are being added every year a few of which are mentioned below.

Other products: The gamma source can be utilized semi commercially for de contamination of the spices spirulina, enzymes, antibiotics, peat soil and pharmaceutical products .

Methods of Sterilization

Five main methods are used for sterilization . The method used will depend on the size, amount and composition of the products.

  1. Heat Method: In this method, high temperatures are used ( above 100o C ) in controlled conditions . Dry heat sterilization is carried out by maintaining the product at 150o C for one hour or at 160o C - 170o C for not less than 2 hours. This method is suitable for heat resistant products like glassware, metal ware some chemicals, oils etc
  2. Moist heat sterilization is carried out air free with saturated steam under pressure at not less than 121o C for a minimum holding time of 15 minutes . Other temperature time combination may be employed depending upon the stability of the product.
  3. ETO ( Ethylene Oxide sterilization ) is carried out with pure gas or that mixed with suitable inert gas like CO2, or halogenated hydrocarbon. This process is used for heat and radiation sensitive materials
  4. Filtration method: Can be applied to certain products and is costly
  5. Sterilant Chemical method: Has limitation in use and chemicals can be harmful to for the products.
  6. Sterilization By Radiation: Sterilization of medical products and other pharmaceuticals with radiation has now become an acceptable practice all over the world .
  7. The advantages of radiation sterilization:
    1. Is more reliable and has a high degree of sterilization quality
    2. This is a cold method , and there is no temperature rise , therefore can be used for temperature sensitive material.
    3. The gamma ray penetrates any final packing material , therefore the product gets sterilized within the package and the sterility is retained indefinitely
    4. The penetration during radiation sterilization is uniform..
    5. It does not require post sterilization microbiological quality control.

Disadvantage

Some glass on irradiation may undergo colour change. Some formulations of plastics may undergo chemical changes

Developments

A semi commercial project is also under construction at AERE , Savar . With an estimated start date of March- April 2009. this facility will have a source strength of 350 KCi, which will allow volume sterilization and much faster.

Others

Rates/ Charges for Irradiation
DoseCharge in Taka
10.5-5 KGy300.00 / cft
26-10 KGy350.00 / cft
311-20 KGy450.00 / cft
421-25 KGy500.00 / cft
526-40 KGy600.00 / cft
6Package of medical products 5.00 / cft

Contact us:
Director, Institute of Food and Radiation Biology
Atomic Energy Research Establishment ( AERE )
Ganakbari, Savar

Tel , Director : 88-02-7701340
AERE Fax: 88-02-7701337, 88-02-7701620.

Or
Head, Microbiology and Industrial Irradiation Division, IFRB
Tel: 88-02-7702033



Copyright © Atomic Energy Research Establishment, Ganakbari, Savar, P.O. Box No. 3787, Dhaka-1000, Bangladesh.
Telephone 880-2- 7701252; Facsimilie 880-2-7701337.